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Image Search Results
Journal: British Journal of Cancer
Article Title: Loss of Coxsackie and adenovirus receptor downregulates α -catenin expression
doi: 10.1038/sj.bjc.6605331
Figure Lengend Snippet: Impact of CAR and α -catenin on cellular morphology. Cells after CAR knockdown appear round and smaller compared with controls (DLD1) or display less intercellular attachment sites (IEC-6). In matrigel, cells after CAR knockdown form amorphous clusters in contrast to the organised-appearing formations of matching controls. Ectopic ‘re’-expression of α -catenin partially reverses the effects seen after CAR knockdown when grown as a monolayer, and particularly results in organised cell formations similar to those of vector controls when cultured in matrigel. Images show representative results for DLD1 ( A ) and IEC-6 ( B ).
Article Snippet: The
Techniques: Knockdown, Expressing, Plasmid Preparation, Cell Culture
Journal: British Journal of Cancer
Article Title: Loss of Coxsackie and adenovirus receptor downregulates α -catenin expression
doi: 10.1038/sj.bjc.6605331
Figure Lengend Snippet: Functional impact of CAR downregulation and α -catenin ‘re’-expression in DLD1 and IEC-6 cell lines. Proliferation ( A ), migration ( B ), and invasion ( C ) in DLD1 and IEC-6 were determined after CAR knockdown and ‘re’-expression of α -catenin in comparison with controls.
Article Snippet: The
Techniques: Functional Assay, Expressing, Migration, Knockdown, Comparison